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Recommendations for use of Chemotherapy

Acknowledgements

Membership of NBOCC* Chemotherapy Working Group

This guideline was developed by a multidisciplinary working group convened by NBOCC*.

Associate Professor Martin Stockler Medical Oncologist (Chair)
Dr Arlene Chan Medical Oncologist
Ms Sally Crossing AM Consumer Representative
Ms Jennifer Muller Consumer Representative
Ms Kathy Watty Breast Nurse Coordinator
Dr Nicholas Wilcken Medical Oncologist

* In July 2011, National Breast and Ovarian Cancer Centre (NBOCC) amalgamated with Cancer Australia to form a single national agency, Cancer Australia, to provide leadership in cancer control and improve outcomes for Australians affected by cancer.

Membership of NBOCC* Advanced Breast Cancer Guidelines Working Group

The development of this guideline was overseen by a multidisciplinary working group convened
by NBOCC*: Dr Karen Luxford (Facilitator), Dr David Blakey, Professor Phyllis Butow, Ms Helen
Collyer (deceased), Ms Sally Crossing AM, Associate Professor Jane Dahlstrom, Dr Craig Murphy,
Ms Janet Rice, Dr Catherine Shannon, Ms Ann Town (deceased), Professor Patsy Yates.

* In July 2011, National Breast and Ovarian Cancer Centre (NBOCC) amalgamated with Cancer Australia to form a single national agency, Cancer Australia, to provide leadership in cancer control and improve outcomes for Australians affected by cancer.

NBOCC* Staff

Ms Ornella Care Program Manager
Ms Emma Lonsdale Project Officer
Ms Alison Pearce Program Manager

Systematic Reviews

NBOCC* gratefully acknowledges the work of Dr Nicholas Wilcken and Dr Rachel Dear at
Westmead Hospital and Dr Agnes Vitry at the University of South Australia Sansom Institute in
developing systematic reviews, which informed this guideline.

* In July 2011, National Breast and Ovarian Cancer Centre (NBOCC) amalgamated with Cancer Australia to form a single national agency, Cancer Australia, to provide leadership in cancer control and improve outcomes for Australians affected by cancer.

External Review

NBOCC* acknowledges those who gave their time to provide comment on the draft guideline
recommendations as part of the external review process.

* In July 2011, National Breast and Ovarian Cancer Centre (NBOCC) amalgamated with Cancer Australia to form a single national agency, Cancer Australia, to provide leadership in cancer control and improve outcomes for Australians affected by cancer.

Acknowledgement

The National Breast Cancer Foundation provided funding for the development of this guideline.

Pharmaceutical Benefits Scheme listings for drugs mentioned in this guideline for the
treatment of advanced or metastatic breast cancer are available at www.pbs.gov.au

The Herceptin® Program

Trastuzumab is subsidised (via The Herceptin® Program funded by the Australian Government:
www.medicareaustralia.gov.au) for the treatment of patients with HER2-positive metastatic
breast cancer:

  • in combination with taxanes, for patients who have not received chemotherapy for metastatic disease, or
  • as monotherapy, for treatment of patients who have received one or more chemotherapy regimen(s) for metastatic disease.

Development process

Priority topic areas for NBOCC* guideline development are determined in consultation with key stakeholders including experts in relevant disciplines and consumer representatives. A specific multidisciplinary Working Group, including consumers, is established for each topic identified and is involved in all aspects of guideline development. A systematic evidence review is undertaken for each guideline. All members are asked to declare any conflicts of interest and these declarations are recorded.  The content of the guideline is not influenced by any external funding body. The guideline is reviewed externally by key stakeholders and the wider community and endorsement is sought from relevant professional colleges and groups in Australia.

* In July 2011, National Breast and Ovarian Cancer Centre (NBOCC) amalgamated with Cancer Australia to form a single national agency, Cancer Australia, to provide leadership in cancer control and improve outcomes for Australians affected by cancer.

Recommendations for use of chemotherapy for the treatment of advanced breast cancer
was prepared and produced by:

National Breast and Ovarian Cancer Centre*
Level 1 Suite 103/355 Crown Street Surry Hills NSW 2010
Tel: +61 2 9357 9400 Fax: +61 2 9357 9477 Freecall 1800 624 973
Website: www.nbocc.org.au

© Cancer Australia 2011
ISBN Print: 978-1-74127-136-2 Online: 978-1-74127-137-9 CIP: 616.99449061

This work is copyright. Apart from any use as permitted under the Copyright Act 1968, no part
might be reproduced by any process without prior written permission from National Breast
and Ovarian Cancer Centre*. Requests and enquiries concerning reproduction and rights should
be addressed to the Corporate Communications Manager, National Breast and Ovarian
Cancer Centre*.

Copies of this resource can be downloaded from the National Breast and Ovarian Cancer
Centre* website: www.nbocc.org.au.

Recommended citation
National Breast and Ovarian Cancer Centre*. Recommendations for use of chemotherapy for the
treatment of advanced breast cancer. National Breast and Ovarian Cancer Centre*, Surry Hills,
NSW, 2010.

Disclaimer
National Breast and Ovarian Cancer Centre* does not accept any liability for any injury, loss or
damage incurred by use of or reliance on the information. National Breast and Ovarian Cancer
Centre* develops material based on the best available evidence, however it cannot guarantee
and assumes no legal liability or responsibility for the currency or completeness
of the information.

National Breast and Ovarian Cancer Centre* is funded by the Australian Government
Department of Health and Ageing.

* In July 2011, National Breast and Ovarian Cancer Centre (NBOCC) amalgamated with Cancer Australia to form a single national agency, Cancer Australia, to provide leadership in cancer control and improve outcomes for Australians affected by cancer.

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